| 1 |
Directed evolution of theB. subtilisnitroreductase YfkO improves activation of the PET-capable probe SN33623 and CB1954 prodrug
Rich MH, Sharrock AV, Ashoorzadeh A, Patterson AV, Smaill JB, Ackerley DF
Biotechnology Letters, 43(1), 203, 2021 |
| 2 |
The indigoidine synthetase BpsA provides a colorimetric ATP assay that can be adapted to quantify the substrate preferences of other NRPS enzymes
Brown AS, Calcott MJ, Collins VM, Owen JG, Ackerley DF
Biotechnology Letters, 42(12), 2665, 2020 |
| 3 |
A cofactor consumption screen identifies promising NfsB family nitroreductases for dinitrotoluene remediation
Williams EM, Sharrock AV, Rylott EL, Bruce NC, MacKichan JK, Ackerley DF
Biotechnology Letters, 41(10), 1155, 2019 |
| 4 |
Evaluation of NfsA-like nitroreductases from Neisseria meningitidis and Bartonella henselae for enzyme-prodrug therapy, targeted cellular ablation, and dinitrotoluene bioremediation
Rich MH, Sharrock AV, Hall KR, Ackerley DF, MacKichan JK
Biotechnology Letters, 40(2), 359, 2018 |
| 5 |
A gain-of-function positive-selection expression plasmid that enables high-efficiency cloning
Prosser GA, Williams EM, Sissons JA, Walmsley KE, Parker MR, Ackerley DF
Biotechnology Letters, 37(2), 383, 2015 |
| 6 |
Genetic manipulation of non-ribosomal peptide synthetases to generate novel bioactive peptide products
Calcott MJ, Ackerley DF
Biotechnology Letters, 36(12), 2407, 2014 |
| 7 |
Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein
Jung J, Bashiri G, Johnston JM, Brown AS, Ackerley DF, Baker EN
Journal of Structural Biology, 188(3), 274, 2014 |
