화학공학소재연구정보센터
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No. Article
1 DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H
Nature, 592(7856), 778, 2021
2 N-terminal degradation activates the NLRP1B inflammasome
Chui AJ, Okondo MC, Rao SD, Gai K, Griswold AR, Johnson DC, Ball DP, Taabazuing CY, Orth EL, Vittimberga BA, Bachovchin DA
Science, 364(6435), 82, 2019
3 LACTB is a tumour suppressor that modulates lipid metabolism and cell state
Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA
Nature, 543(7647), 681, 2017
4 Competitive Activity-Based Protein Profiling Identifies Aza-beta-Lactams as a Versatile Chemotype for Serine Hydrolase Inhibition
Zuhl AM, Mohr JT, Bachovchin DA, Niessen S, Hsu KL, Berlin JM, Dochnahl M, Lopez-Alberca MP, Fu GC, Cravatt BF
Journal of the American Chemical Society, 134(11), 5068, 2012
5 Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes
Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF
Journal of the American Chemical Society, 134(25), 10345, 2012
6 A Substrate-Free Activity-Based Protein Profiling Screen for the Discovery of Selective PREPL Inhibitors
Lone AM, Bachovchin DA, Westwood DB, Speers AE, Spicer TP, Fernandez-Vega V, Chase P, Hodder PS, Rosen H, Cravatt BF, Saghatelian A
Journal of the American Chemical Society, 133(30), 11665, 2011
7 Potent and Selective Inhibitors of Glutathione S-Transferase Omega 1 That Impair Cancer Drug Resistance
Tsuboi K, Bachovchin DA, Speers AE, Spicer TP, Fernandez-Vega V, Hodder P, Rosen H, Cravatt BF
Journal of the American Chemical Society, 133(41), 16605, 2011