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Bacterial Quorum Sensing Signals Self-Assemble in Aqueous Media to Form Micelles and Vesicles: An Integrated Experimental and Molecular Dynamics Study Gahan CG, Patel SJ, Boursier ME, Nyffeler KE, Jennings J, Abbott NL, Blackwell HE, Van Lehn RC, Lynn DM Journal of Physical Chemistry B, 124(18), 3616, 2020 |
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Conformational Switch to a beta-Turn in a Staphylococcal Quorum Sensing Signal Peptide Causes a Dramatic Increase in Potency Vasquez JK, West KHJ, Yang T, Polaske TJ, Cornilescu G, Tonelli M, Blackwell HE Journal of the American Chemical Society, 142(2), 750, 2020 |
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Slippery Liquid-Infused Porous Surfaces that Prevent Microbial Surface Fouling and Kill Non-Adherent Pathogens in Surrounding Media: A Controlled Release Approach Manna U, Raman N, Welsh MA, Zayas-Gonzalez YM, Blackwell HE, Palecek SP, Lynn DM Advanced Functional Materials, 26(21), 3599, 2016 |
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Small Molecule Disruption of Quorum Sensing Cross-Regulation in Pseudomonas aeruginosa Causes Major and Unexpected Alterations to Virulence Phenotypes Welsh MA, Eibergen NR, Moore JD, Blackwell HE Journal of the American Chemical Society, 137(4), 1510, 2015 |
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A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design Moore JD, Rossi FM, Welsh MA, Nyffeler KE, Blackwell HE Journal of the American Chemical Society, 137(46), 14626, 2015 |
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Highly Potent Inhibitors of Quorum Sensing in Staphylococcus aureus Revealed Through a Systematic Synthetic Study of the Group-III Autoinducing Peptide Tal-Gan Y, Stacy DM, Foegen MK, Koenig DW, Blackwell HE Journal of the American Chemical Society, 135(21), 7869, 2013 |
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Structural Characterization of Native Autoinducing Peptides and Abiotic Analogues Reveals Key Features Essential for Activation and Inhibition of an AgrC Quorum Sensing Receptor in Staphylococcus aureus Tal-Gan Y, Ivancic M, Cornilescu G, Cornilescu CC, Blackwell HE Journal of the American Chemical Society, 135(49), 18436, 2013 |
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Introduction to Bacterial Signals and Chemical Communication Blackwell HE, Fuqua C Chemical Reviews, 111(1), 1, 2011 |
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Extraordinarily Robust Polyproline Type I Peptoid Helices Generated via the Incorporation of alpha-Chiral Aromatic N-1-Naphthylethyl Side Chains Stringer JR, Crapster JA, Guzei IA, Blackwell HE Journal of the American Chemical Society, 133(39), 15559, 2011 |
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Chemical Modification of Reactive Multilayered Films Fabricated from Poly(2-alkenyl azlactone)s: Design of Surfaces that Prevent or Promote Mammalian Cell Adhesion and Bacterial Biofilm Growth Buck ME, Breitbach AS, Belgrade SK, Blackwell HE, Lynn DM Biomacromolecules, 10(6), 1564, 2009 |