| 1 |
Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step
Xu JL, Zheng S, Dawood Z, Hill C, Jin WX, Xu XK, Ding J, Borys MC, Ghose S, Li ZJ, Pendse G
Biotechnology and Bioengineering, 118(9), 3334, 2021 |
| 2 |
Use of 5-Thio-L-Fucose to modulate binding affinity of therapeutic proteins
Zimmermann M, Nguyen M, Schultheiss CM, Kolmar H, Zimmer A
Biotechnology and Bioengineering, 118(5), 1818, 2021 |
| 3 |
Understanding the effect of high gas entrance velocity on Chinese hamster ovary (CHO) cell culture performance and its implications on bioreactor scale-up and sparger design
Chaudhary G, Luo RB, George M, Tescione L, Khetan A, Lin H
Biotechnology and Bioengineering, 117(6), 1684, 2020 |
| 4 |
Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events
Fratz-Berilla EJ, Angart P, Graham RJ, Powers DN, Mohammad A, Kohnhorst C, Faison T, Velugula-Yellela SR, Trunfio N, Agarabi C
Biotechnology and Bioengineering, 117(9), 2802, 2020 |
| 5 |
Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures
Fratz-Berilla EJ, Faison T, Kohnhorst CL, Velugula-Yellela SR, Powers DN, Brorson K, Agarabi C
Biotechnology and Bioengineering, 116(12), 3242, 2019 |
| 6 |
Predicting industrial-scale cell culture seed trains-A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method
Rodriguez TH, Posch C, Schmutzhard J, Stettner J, Weihs C, Portner R, Frahm B
Biotechnology and Bioengineering, 116(11), 2944, 2019 |
| 7 |
Consequences of trace metal variability and supplementation on Chinese hamster ovary (CHO) cell culture performance: A review of key mechanisms and considerations
Graham RJ, Bhatia H, Yoon S
Biotechnology and Bioengineering, 116(12), 3446, 2019 |
| 8 |
Real-time monitoring and control of CHO cell apoptosis by in situ multifrequency scanning dielectric spectroscopy
Ma FD, Zhang A, Chang D, Velev OD, Wiltberger K, Kshirsagar R
Process Biochemistry, 80, 138, 2019 |
| 9 |
Intracellular response to process optimization and impact on productivity and product aggregates for a high-titer CHO cell process
Handlogten MW, Lee-O'Brien A, Roy G, Levitskaya SV, Venkat R, Singh S, Ahuja S
Biotechnology and Bioengineering, 115(1), 126, 2018 |
| 10 |
Cell-controlled hybrid perfusion fed-batch CHO cell process provides significant productivity improvement over conventional fed-batch cultures
Hiller GW, Ovalle AM, Gagnon MP, Curran ML, Wang WG
Biotechnology and Bioengineering, 114(7), 1438, 2017 |
