검색결과 : 13건
| No. | Article |
|---|---|
| 1 |
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis Chaurasia B, Tippetts TS, Monibas RM, Liu JQ, Li Y, Wang LP, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen XL, Yao J, Nunes CN, Howard AD, Wang LS, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA Science, 365(6451), 386, 2019 |
| 2 |
Use of a QM/MM-Based FEP Method to Evaluate the Anomalous Hydration Behavior of Simple Alkyl Amines and Amides: Application to the Design of FBPase Inhibitors for the Treatment of Type-2 Diabetes Reddy MR, Singh UC, Erion MD Journal of the American Chemical Society, 133(21), 8059, 2011 |
| 3 |
Relative binding affinities of fructose-1,6-bisphosphatase inhibitors calculated using a quantum mechanics-based free energy perturbation method Reddy MR, Erion MD Journal of the American Chemical Society, 129(30), 9296, 2007 |
| 4 |
Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity Erion MD, Dang Q, Reddy MR, Kasibhatla SR, Huang J, Lipscomb WN, van Poelje PD Journal of the American Chemical Society, 129(50), 15480, 2007 |
| 5 |
Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes Dang Q, Kasibhatla SR, Reddy KR, Jiang T, Reddy MR, Potter SC, Fujitaki JM, van Poelje PD, Huang J, Lipscomb WN, Erion MD Journal of the American Chemical Society, 129(50), 15491, 2007 |
| 6 |
Design, synthesis, and characterization of a series of cytochrome P-450 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver Erion MD, Reddy KR, Boyer SH, Matelich MC, Gornez-Galeno J, Lemus RH, Ugarkar BG, Colby TJ, Schanzer J, van Poelje PD Journal of the American Chemical Society, 126(16), 5154, 2004 |
| 7 |
Development of a quantum mechanics-based free-energy perturbation method: Use in the calculation of relative solvation free energies Reddy MR, Singh UC, Erion MD Journal of the American Chemical Society, 126(20), 6224, 2004 |
| 8 |
Isolation of a family of organic anion transporters from human liver and kidney Sun W, Wu RR, van Poelje PD, Erion MD Biochemical and Biophysical Research Communications, 283(2), 417, 2001 |
| 9 |
Calculation of relative binding free energy differences for fructose 1,6-bisphosphatase inhibitors using the thermodynamic cycle perturbation approach Reddy MR, Erion MD Journal of the American Chemical Society, 123(26), 6246, 2001 |
| 10 |
Computer-assisted scanning of ligand interactions: Analysis of the fructose 1,6-bisphosphatase-AMP complex using free energy calculations Erion MD, van Poelje PD, Reddy MR Journal of the American Chemical Society, 122(25), 6114, 2000 |