검색결과 : 8건
| No. | Article |
|---|---|
| 1 |
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas (vol 550, pg 133, 2017) Lu HZ, Liu SJ, Zhang G, Wu B, Zhu YY, Frederick DT, Hu Y, Zhong WQ, Randell S, Sadek N, Zhang W, Chen G, Cheng CR, Zeng JW, Wu LW, Zhang J, Liu XM, Xu W, Krepler C, Sproesser K, Xiao M, Miao BC, Liu JL, Song CD, Liu JY, Karakousis GC, Schuchter LM, Lu YL, Mills G, Cong YS, Chernoff J, Guo J, Boland GM, Sullivan RJ, Wei Z, Field J, Amaravadi RK, Flaherty KT, Herlyn M, Xu XW, Guo W Nature, 565(7738), E4, 2019 |
| 2 |
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas Lu HZ, Liu SJ, Zhang G, Wu B, Zhu YY, Frederick DT, Hu Y, Zhong WQ, Randell S, Sadek N, Zhang W, Chen G, Cheng CR, Zeng JW, Wu LW, Zhang J, Liu XM, Xu W, Krepler C, Sproesser K, Xiao M, Miao BC, Liu JL, Song CD, Liu JY, Karakousis GC, Schuchter LM, Lu YL, Mills G, Cong YS, Chernoff J, Guo J, Boland GM, Sullivan RJ, Wei Z, Field J, Amaravadi RK, Flaherty KT, Herlyn M, Xu XW, Guo W Nature, 550(7674), 133, 2017 |
| 3 |
sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, Meeth K, Tang HY, Yin XF, Wood WH, Lehrmann E, Becker KG, Flaherty KT, Frederick DT, Wargo JA, Cooper ZA, Tetzlaff MT, Hudgens C, Aird KM, Zhang RG, Xu XW, Liu Q, Bartlett E, Karakousis G, Eroglu Z, Lo RS, Chan M, Menzies AM, Long GV, Johnson DB, Sosman J, Schilling B, Schadendorf D, Speicher DW, Bosenberg M, Ribas A, Weeraratna AT Nature, 532(7598), 250, 2016 |
| 4 |
sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance (vol 532, pg 250, 2016) Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, Meeth K, Tang HY, Yin XF, Wood WH, Lehrmann E, Becker KG, Flaherty KT, Frederick DT, Wargo JA, Cooper ZA, Tetzlaff MT, Hudgens C, Aird KM, Zhang RG, Xu XW, Liu Q, Bartlett E, Karakousis G, Eroglu Z, Lo RS, Chan M, Menzies AM, Long GV, Johnson DB, Sosman J, Schilling B, Schadendorf D, Speicher DW, Bosenberg M, Ribas A, Weeraratna AT Nature, 537(7619), -, 2016 |
| 5 |
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CGK, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jane-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA Science, 352(6282), 189, 2016 |
| 6 |
A melanocyte lineage program confers resistance to MAP kinase pathway inhibition Johannessen CM, Johnson LA, Piccioni F, Townes A, Frederick DT, Donahue MK, Narayan R, Flaherty KT, Wargo JA, Root DE, Garraway LA Nature, 504(7478), 138, 2013 |
| 7 |
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian ZR, Du JY, Davis A, Mongare MM, Gould J, Frederick DT, Cooper ZA, Chapman PB, Solit DB, Ribas A, Lo RS, Flaherty KT, Ogino S, Wargo JA, Golub TR Nature, 487(7408), 500, 2012 |
| 8 |
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E) Poulikakos PI, Persaud Y, Janakiraman M, Kong XJ, Ng C, Moriceau G, Shi HB, Atefi M, Titz B, Gabay MT, Salton M, Dahlman KB, Tadi M, Wargo JA, Flaherty KT, Kelley MC, Misteli T, Chapman PB, Sosman JA, Graeber TG, Ribas A, Lo RS, Rosen N, Solit DB Nature, 480(7377), 387, 2011 |