1 |
A surprisingly stable macrochelate formed from the reaction of cis dinuclear platinum antitumor compounds with reduced glutathione Oehlsen ME, Hegmans A, Qu Y, Farrell N Inorganic Chemistry, 44(9), 3004, 2005 |
2 |
Synthesis, characterization, and cytotoxicity of a novel highly charged trinuclear platinum compound. Enhancement of cellular uptake with charge Harris AL, Yang XH, Hegmans A, Povirk L, Ryan JJ, Kelland L, Farrell NP Inorganic Chemistry, 44(26), 9598, 2005 |
3 |
Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure Hegmans A, Berners-Price SJ, Davies MS, Thomas DS, Humphreys AS, Farrell N Journal of the American Chemical Society, 126(7), 2166, 2004 |
4 |
Kinetic and equilibria studies of the aquation of the trinuclear platinum phase 11 anticancer agent [{trans-PtCl(NH3)(2)}(2){mu-trans-Pt(NH3)(2)(NH2(CH2)(6)NH2)(2)}](4+) (BBR3464) Davies MS, Thomas DS, Hegmans A, Berners-Price SJ, Farrell N Inorganic Chemistry, 41(5), 1101, 2002 |
5 |
Novel approaches to polynuclear platinum pro-drugs. Selective release of cytotoxic platinum spermidine species through hydrolytic cleavage of carbamates Hegmans A, Qu Y, Kelland LR, Roberts JD, Farrell N Inorganic Chemistry, 40(24), 6108, 2001 |
6 |
Synthetic ways to tris(nucleobase) complexes derived from cis-diamineplatinum(II) and a platinum(II) complex containing four different ligands, three of which are nucleobases Hegmans A, Sabat M, Baxter I, Freisinger E, Lippert B Inorganic Chemistry, 37(19), 4921, 1998 |