검색결과 : 3건
| No. | Article |
|---|---|
| 1 |
Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant Quirke JCK, Rajasekaran P, Sarpe V, Sonousi A, Osinnii I, Gysin M, Haldimann K, Fang QJ, Shcherbakov D, Hobbie SN, Sha SH, Schacht J, Vasella A, Bottger EC, Crich D Journal of the American Chemical Society, 142(1), 530, 2020 |
| 2 |
Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens Matsushita T, Sati GC, Kondasinghe N, Pirrone MG, Kato T, Waduge P, Kumar HS, Sanchon AC, Dobosz-Bartoszek M, Shcherbakov D, Juhas M, Hobbie SN, Schrepfer T, Chow CS, Polikanov YS, Schacht J, Vasella A, Bottger EC, Crich D Journal of the American Chemical Society, 141(12), 5051, 2019 |
| 3 |
Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues: Importance of the Configuration at the 6 '-Position and Differences between the 6 '-Amino and Hydroxy Series Mandhapati AR, Yang GY, Kato T, Shcherbakov D, Hobbie SN, Vasella A, Bottger EC, Crich D Journal of the American Chemical Society, 139(41), 14611, 2017 |