검색결과 : 6건
| No. | Article |
|---|---|
| 1 |
Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity Erion MD, Dang Q, Reddy MR, Kasibhatla SR, Huang J, Lipscomb WN, van Poelje PD Journal of the American Chemical Society, 129(50), 15480, 2007 |
| 2 |
Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes Dang Q, Kasibhatla SR, Reddy KR, Jiang T, Reddy MR, Potter SC, Fujitaki JM, van Poelje PD, Huang J, Lipscomb WN, Erion MD Journal of the American Chemical Society, 129(50), 15491, 2007 |
| 3 |
Design, synthesis, and characterization of a series of cytochrome P-450 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver Erion MD, Reddy KR, Boyer SH, Matelich MC, Gornez-Galeno J, Lemus RH, Ugarkar BG, Colby TJ, Schanzer J, van Poelje PD Journal of the American Chemical Society, 126(16), 5154, 2004 |
| 4 |
Isolation of a family of organic anion transporters from human liver and kidney Sun W, Wu RR, van Poelje PD, Erion MD Biochemical and Biophysical Research Communications, 283(2), 417, 2001 |
| 5 |
Computer-assisted scanning of ligand interactions: Analysis of the fructose 1,6-bisphosphatase-AMP complex using free energy calculations Erion MD, van Poelje PD, Reddy MR Journal of the American Chemical Society, 122(25), 6114, 2000 |
| 6 |
Discovery of AMP mimetics that exhibit high inhibitory potency and specificity for AMP deaminase Erion MD, Kasibhatla SR, Bookser BC, van Poelje PD, Reddy MR, Gruber HE, Appleman JR Journal of the American Chemical Society, 121(2), 308, 1999 |