Biotechnology and Bioengineering

Biotechnology and Bioengineering, Vol.118, No.9 Entire volume, number list

ISSN: 0006-3592 (Print)

In this Issue (31 articles)

3275 - 3286	White paper on high-throughput process development for integrated continuous biomanufacturing Sao Pedro MN, Silva TC, Patil R, Ottens M
3287 - 3301	Pilot-scale demonstration of an end-to-end integrated and continuous biomanufacturing process Coolbaugh MJ, Varner CT, Vetter TA, Davenport EK, Bouchard B, Fiadeiro M, Tugcu N, Walther J, Patil R, Brower K
3302 - 3312	End-to-end collaboration to transform biopharmaceutical development and manufacturing Erickson J, Baker J, Barrett S, Brady C, Brower M, Carbonell R, Charlebois T, Coffman J, Connell-Crowley L, Coolbaugh M, Fallon E, Garr E, Gillespie C, Hart R, Haug A, Nyberg G, Phillips M, Pollard D, Qadan M, Ramos I, Rogers K, Schaefer G, Walther J, Lee K
3313 - 3322	Process development and optimization of continuous capture with three-column periodic counter-current chromatography Shi C, Zhang QL, Jiao B, Chen XJ, Chen R, Gong W, Yao SJ, Lin DQ
3323 - 3333	The design basis for the integrated and continuous biomanufacturing framework Coffman J, Bibbo K, Brower M, Forbes R, Guros N, Horowski B, Lu R, Mahajan R, Patil U, Rose S, Shultz J
3334 - 3347	Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step Xu JL, Zheng S, Dawood Z, Hill C, Jin WX, Xu XK, Ding J, Borys MC, Ghose S, Li ZJ, Pendse G
3348 - 3358	Development of a platform process for the production and purification of single-domain antibodies Crowell LE, Goodwine C, Holt CS, Rocha L, Vega C, Rodriguez SA, Dalvie NC, Tracey MK, Puntel M, Wigdorovitz A, Parreno V, Love KR, Cramer SM, Love JC
3359 - 3366	Enhancing protein A productivity and resin utilization within integrated or intensified processes Brinkmann A, Elouafiq S
3367 - 3374	Utilizing bacteriophage to define the minimum residence time within a plug flow reactor Brown MR, Orozco R
3375 - 3381	Continuous capture scale down model: A comparison of a continuous and a discrete approach Seidel JC, Gobel M, Rodrigues RCD, Kaup NM, Rapp J, Frauenschuh A, Shultz J, Cui HC
3382 - 3394	Media on-demand: Continuous reconstitution of a chemically defined media directly from solids Komuczki D, Dutra G, Gstottner C, Dominguez-Vega E, Jungbauer A, Satzer P
3395 - 3408	Lactoyl leucine and isoleucine are bioavailable alternatives for canonical amino acids in cell culture media Schmidt C, Wehsling M, Le Mignon M, Wille G, Rey Y, Schnellbaecher A, Zabezhinsky D, Fischer M, Zimmer A
3409 - 3419	An effective computational-screening strategy for simultaneously improving both catalytic activity and thermostability of alpha-l-rhamnosidase Li LJ, Li WJ, Gong JY, Xu YY, Wu ZY, Jiang ZD, Cheng YS, Li QB, Ni H
3420 - 3434	Analysis and optimal design of batch and two-column continuous chromatographic frontal processes for monoclonal antibody purification Shi C, Vogg S, Lin DQ, Sponchioni M, Morbidelli M
3435 - 3446	Rapid optimization of processes for the integrated purification of biopharmaceuticals Crowell LE, Rodriguez SA, Love KR, Cramer SM, Love JC
3447 - 3459	Probabilistic model by Bayesian network for the prediction of antibody glycosylation in perfusion and fed-batch cell cultures Zhang L, Wang ML, Castan A, Hjalmarsson H, Chotteau V
3460 - 3467	Flow management strategies for a connected purification process Goebel M, Rodrigues R, Pampel L, Rapp J, Shultz J, Cui HC
3468 - 3485	End-to-end continuous bioprocessing: Impact on facility design, cost of goods, and cost of development for monoclonal antibodies Mahal H, Branton H, Farid SS
3486 - 3498	A novel approach to residence time distribution characterization in a mAb continuous process Brantley T, Bogue J, Denny K, Elouafiq S, Madren S, Nakhle B, Khattak S
3499 - 3510	Antibody capture process based on magnetic beads from very high cell density suspension Brechmann NA, Schwarz H, Eriksson PO, Eriksson K, Shokri A, Chotteau V
3511 - 3521	The effects of flux on the clearance of minute virus of mice during constant flux virus filtration Fan R, Namila F, Sansongko D, Wickramasinghe SR, Jin M, Kanani D, Qian XH
3522 - 3532	Oncolytic virus purification with periodic counter-current chromatography Mendes JP, Silva RJS, Berg M, Mathiasson L, Peixoto C, Alves PM, Carrondo MJT
3533 - 3544	Process intensification to produce a difficult-to-express therapeutic enzyme by high cell density perfusion or enhanced fed-batch Sarnlund S, Jiang Y, Chotteau V
3545 - 3558	A scalable bubble-free membrane aerator for biosurfactant production Bongartz P, Bator I, Baitalow K, Keller R, Tiso T, Blank LM, Wessling M
3559 - 3568	Stretch-driven microfluidic chip for nucleic acid detection Li X, Zhao XY, Yang WH, Xu F, Chen BL, Peng JW, Huang JJ, Mi SL
3569 - 3580	Analysis of filtration behavior using integrated column chromatography followed by virus filtration Shirataki H, Yokoyama Y, Taniguchi H, Azeyanagi M
3581 - 3592	Process intensification for the production of yellow fever virus-like particles as potential recombinant vaccine antigen Alvim RGF, Lima TM, Silva JL, de Oliveira GAP, Castilho LR
3593 - 3603	Online monitoring and control of upstream cell culture process using 1D and 2D-LC with SegFlow interface Chemmalil L, Wasalathanthri DP, Zhang X, Kuang JE, Shao C, Barbour R, Bhavsar S, Prabhakar T, Knihtila R, West J, Puri N, McHugh K, Rehmann MS, He Q, Xu JL, Borys MC, Ding JL, Li ZJ
3604 - 3609	Continued insights into virus clearance validation across continuous capture chromatography Angelo JM, Potter K, Muller-Spath T, Xu XK, Li ZJ, Ghose S
3610 - 3617	Online monitoring of hiPSC expansion and hepatic differentiation in 3D culture by dielectric spectroscopy Isidro IA, Vicente P, Pais DAM, Almeida JI, Domingues M, Abecasis B, Zapata-Linares N, Rodriguez-Madoz JR, Prosper F, Aspegren A, Alves PM, Serra M
3618 - 3623	Improving an intensified and integrated continuous bioprocess platform for biologics manufacturing Zhou H, Fang MY, Zheng X, Zhou WC