The presence of heavy metals in the environment represent a very significant and long-term environmental hazard. Many industries such as electroplating industry, organic inorganic chemical, petrochemicals, fertilizer etc discharge effluent containing high level of metal ions. In the present paper, a study on the adsorption of Cu(II), Cr(VI), Fe(II) and Ni(II) by an agricultural by-product i.e. powder of Bajra was carried out. The effects of solution pH, initial concentration, adsorbent amount, temperature and contact time were studied. In batch experiments, adsorption of these metal ions increases with decrease in initial concentration of metal ion and adsorbent dosage. Measured values have been found to follow Langmuir and Freundlich adsorption isotherms.