2-Pyridyliminosalicylcellulose has been used for the sorption and estimation of lead(II) by column and batch techniques. The distribution coefficient (D) was found to be 4.3x10(2) for the lead ion. The detection limit was found to be 3.82 ng mL(-1) and the breakthrough volume was 20 mL. The present matrix coupled with FAAS has been used to enrich and determine the lead ions in natural and wastewater (RSD similar to 2.52-3.50%) and egg samples (RSD similar to 2.73%). The method is simple, rapid and relatively free from interference and satisfactorily applied foe the estimation of lead (similar to 98% recovery) in natural, wastewater and egg samples.