The processing conditions that exert influence on the occurrence of breakthrough during sandwich injection molding were investigated. A spiral flow mold mounted on a twin-barrel injection machine fitted with a single nozzle was used. The effect of mold cavity thickness and the effects of skin material cylinder temperature on skin material viscosity, melt strength, and drawing ratio were considered. Scanning electron microscopy was used to study the morphology of the skin material at the flow front. It was found that the flow length at core expansion region increased and breakthrough phenomenon was delayed as the thickness of the mold cavity increased. When cylinder temperature is increased, the viscosity is lowered and the flow front of the skin material extends with greater ease when pushed by the core material, thus, a greater core volume can be accommodated. As the flow front progresses, the tendency is that the skin material becomes thinner Polishing and etching followed by SEM examination of the skin material at the flow front revealed that the skin material is oriented perpendicular to the flow direction and the extent of orientation increases with increasing cylinder temperature. This further supported the observation that the deformation ratio and drawing ratio increased with increasing cylinder temperature.