The paper summarises the present abilities of the models of Computational Fluid Dynamics (CFD) to simulate the processes from the area of interest of chemical and process engineering. Laminar and turbulent flow processes carried out in the single- and multiphase systems are considered. Methods applied to model the course of chemical reactions and precipitation precresses are presented and discussed as well with particular emphasis on prediction of the product quality. Effects of simplifications applied in the CFD models on their accuracy and limitations in their applications are discussed.