In the paper a method of adsorption equilibrium prediction for mixture of water and water immiscible organic compounds, on activated carbon, was presented. The proposed method requires single component isotherm of adsorption and applying of the Dubinin-Astakhov (DA) equation for organic compound and the Dubinin-Serpinsky (DS) equation for water. Satisfactory agreement of computed results with experimental ones approved applicability of the method to binary adsorption capacity prediction of water and organic compound on activated carbon.