Isobaric vapor-liquid equilibria (VLE) data were measured at 101.3 kPa on four oxygenates (acetone, diisopropyl ether, ethanol, and methyl ethyl ketone) separately with hydrocarbon mixtures. Acetone, ethanol, and methyl ethyl ketone were mixed with a five-component hydrocarbon mixture and diisopropyl ether was mixed with a four-component hydrocarbon mixture. Calculations of nonideality of the vapor phase were made with the Soave-Redlich-Kwong equation of state. The vaporization equilibrium ratio of oxygenate in the hydrocarbon mixture was derived. Analysis of the experimental VLE data exhibits a minimum boiling temperature for the systems containing acetone, ethanol, and methyl ethyl ketone. The experimental data have been correlated with the mole fraction of oxygenate using the Redlich-Kister-type and Wisniak-Tamir equations.