The density, viscosity, and refractive index at (298.15, 303.15, and 308.15) K and the speed of sound at 298.15 K in binary mixtures of 1,4-dioxane with 1,2-dichlorobenzene, ethyl acetate, trichloroethylene, 2-chloroethanol, dimethyl acetamide, diethylmalonate, and 1-butanol were measured over the entire mole fraction range of the binary mixtures. Using these data, the excess molar volume, deviations in viscosity, molar refraction, speed of sound, and isentropic compressibility were calculated. The computed quantities were fitted to the Redlich-Kister equation to derive the coefficients and estimate the standard error values.