In this work, a high-pressure visual cell is used to measure bubble and dew pressures and temperatures of a five-component synthetic mixture in the presence Of CO2. The synthetic mixture was gravimetrically prepared and contains octane, hexadecane, methylcyclohexane, cis-decalin, and methylbenzene (toluene). Seven quantities Of CO2 were injected in the synthetic mixture, and for each amount Of CO2 bubble and dew pressures were measured at temperatures ranging from (292.95 to 373.35) K. The corresponding pressures vary between (20 and 165) bar. A total of 61 experimental bubble and dew pressures are reported. The experimental data are compared with results obtained using the PPR78 model in which the temperature-dependent binary interaction parameters are predicted by a group contribution method. Results clearly indicate that the PPR78 model is a good predictive model because the average absolute deviation is about 5.5 bar between experimental and calculated pressures. Results are presented at constant composition in (P, T) diagrams. They are also presented at constant temperature in (P, x(CO2)) diagrams by considering the CO2 and the synthetic mixture as a pseudobinary mixture.