Excess molar volumes, V-m(E), viscosity deviations, Delta eta, deviations in speed of sound, Delta u, and isentropic compressibility, Delta K-s, for the binary mixtures of 1-butanol, C4H9OH with hexadecane, C16H34, and squalane (2,4,6,10,15,19,23-hexamethylteracosane), C30H62, at T = (298.15, 303.15, and 308.15) K and at atmospheric pressure were derived from experimental density, rho, viscosity, eta, and speed of sound, u, data. The calculated excess and deviation functions were further fitted to the polynomial relation to estimate the coefficients and standard errors. The Prigogine-Flory-Patterson (PFP) theory has been used to explain V-m(E), whereas PFP theory with the van der Waals (vdW) potential energy model has also been used for theoretical estimation of u and K-s.