Excess molar enthalpies of five binary systems for ethyl acetoacetate + (1-butanol, + 2-butanol, + 1-pentanol, + water, and + ethyl acetate) at T = (298.15, 313.15, 328.15, 338.15, and 348.15) K and p = 0.1 MPa were determined by a flow-mixing isothermal microcalorimeter. The excess molar enthalpies increase with an increase in the temperature. The experimental data were correlated by the Redlich-Kister equation.