The solubilities of amino acid, 2,4-dinitro-L-phenylalanine in monosolvents water, methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, acetone, ethyl acetate, and 1,2-dichloroethane were measured from (273.15 to 368.15) K at atmospheric pressure using the synthetic method. The solubility was determined by a laser monitoring observation technique. The experimental solubilities were regressed by the modified Apelblat equation with the relative deviation less than 2.5 %.