Solubility equilibria of the chiral N-methylephedrine species in three chiral solvents, (S)-methyl lactate, (S)-propyl lactate, and (S)-butyl lactate, have systematically been studied. Solubility measurements were performed for enantiomeric compositions ranging from 1:1 mixtures to the pure enantiomer and at temperatures between (273 and 298) K. The influence of increasing chain length of the chiral solvents on solubility has been evaluated.