Isothermal vapor-liquid equilibrium (VLE) data have been measured for oligomeric polyoxyethylene dodecanoate (POEDDA) with methanol, ethanol, or propan-2-ol. A synthetic method was used to determine experimentally p-T-x data in the temperature range of (343.2 to 423.2) K. For each binary system, four feed compositions were studied over the concentration range from 0.100 to 0.400 of POEDDA in mole fractions. These new VLE data were fitted to the Antoine equation and also correlated with the nonrandom two-liquid (NRTL) and the universal quasichemical activity coefficient (UNIQUAC) models. The results reveal that the performance of the UNIQUAC and the NRTL models are almost the same. The solvent activities were directly calculated from VLE data and compared to those calculated from the NRTL and the UNIQUAC models.