Acrylated chlorinated low-molecular-weight guayule rubber (ACLMWGR) has been synthesized and characterized with Fourier transform infrared spectroscopy, solid-state nuclear magnetic resonance spectroscopy, and differential scanning calorimetry. We have found that ACLMWGR is useful as a prepolymer in 100% solids ultraviolet (UV) curing wood coatings. The properties of the coatings are equal or superior to coatings prepared from acrylated chlorinated rubber synthesized from commercial masticated natural rubber. However, when low-molecular-weight guayule rubber (LMWGR) serves as the feedstock, the cost of producing ACLMWGR is significantly reduced since no mastication is needed.