Methyl methacrylate, butyl acrylate, acrylic acid, and various amounts of glycidyl methacrylate (GMA) were copolymerized by a semicontinuous seeded emulsion copolymerization to be a four-component copolymer emulsion; the copolymers were characterized using swelling capacity, transmission electron microscopy (TEM), etc. The effect of glycidyl methacrylate and its content on the properties of emulsion and copolymer films was studied. The self-crosslinking reaction of the copolymer was investigated by FTIR and DSC. It was found that the swelling capacity of the crosslinked copolymer films decreased with increase of the glycidyl methacrylate content, the morphology showed a core-shell structure, and the copolymer emulsion possessed a self-crosslinking property.