Wastewater containing pentachlorophenol (PCP) was treated by granular activated carbon (GAC) adsorption and double-dielectric barrier discharge (D-DBD) plasma. A packed bed D-DBD reactor was applied for removal of PCP on GAC and GAC regeneration, where the discharge gap was filled with GAC. PCP degradation efficiency of 65% and GAC regeneration efficiency (RE) of 87% were achieved. Effects of discharge power, treatment time and O-2 flow rate on PCP degradation and GAC regeneration were investigated. Increasing discharge power, treatment time and O-2 flow rate were favorable for PCP degradation, and also contributed to GAC RE. C-Cl bonds in PCP were cleaved by D-DBD plasma. Effect of D-DBD plasma on physical and chemical properties of GAC during GAC regeneration process was characterized by N-2 adsorption and Boehm titration. This study is expected to demonstrate the feasibility of applying D-DBD plasma for efficient organic wastewater treatment by coupling with GAC adsorption.