The catalytic reaction of methanol with hydrogen sulfide at a total pressure of 0.1-1.8 MPa was investigated. The main product at different values of total pressure in the system was methylmercaptan, and the by-products were dimethyl sulfide, dimethyl ether, carbon oxides. An increase in the contact time increased the yields of methylmercaptan and dimethyl sulfide, whereas the yields of dimethyl ether and gases changed slightly. The selectivity for methylmercaptan was approximately constant up to a similar to 95% conversion of methanol. The elevation in temperature increased the reaction rate but barely affected the product formation selectivity. The rate of methanol conversion increases linearly with the hydrogen sulfide concentration and depends on the methanol concentration raised to a power of 0.4-0.5; water retards the process. The selectivity for methylmercaptan decreases, and that for dimethyl sulfide and dimethyl ether increases at an H 2 S to methanol molar ratio below 1.4 : 1, regardless of the value of total pressure. The reaction rate increases with the total pressure raised to a power 0.4-0.5; however, the selectivities for methylmercaptan and by-products remain unchanged.