Although some literature can be found on the behavior of blow tanks, very few studies could be found on the pressure loss at the entry section to a pipeline (henceforth called entry pressure loss) from a top discharge blow tank in a pneumatic conveying system, even though its magnitude can be significant as compared to the total system pressure drop. This article presents the results of an experimental study carried out to assess this entry pressure loss. The results indicate that it is possible to scale up the entry pressure loss based on laboratory-scale tests with a reasonable degree of accuracy.