This article results from an ongoing investigation aimed at developing a new validated test-design procedure for the accurate prediction of pressure drop for dense-phase pneumatic conveying of powders. Models for combined pressure drop coefficient (oKo) for solids-gas mixture were derived using the concept of osuspension densityo by using the steady-state ostraight pipeo pressure drop data between two different tapping locations of the same pipe and also for two different diameter pipes. It was observed that the derived models were different depending on the location of tapping points (for the same pipe) and selected pipe diameters. The derived models were then evaluated by predicting the pressure drop for pipelines with various diameters or lengths (69mm I.D.x168m, 105mm I.D.x168m, 69mm I.D.x554m) for the conveying of power station fly ash. A comparison between the predicted pneumatic conveying characteristics (PCC) and the experimental plots showed that the models resulted in significant over-predictions. In the second part of the article, the osystemo approach of scaleup was evaluated. oTotalo pipeline pressure drop characteristics for test-rig pipelines were scaled up to predict the PCC for larger/longer pipes. It was found that the osystemo approach generally resulted in grossly inaccurate predictions. It was concluded that further studies are needed for a better understanding of the solids-gas flow mechanism under dense-phase conditions.