Studies on the motion of particles in turbulence and interactions between particles and turbulence are extremely significant, which can help us to improve the efficiency of industrial processes. In this article, we investigated the particle distribution and particle-turbulence interaction in a solid-liquid channel flow with the Euler-Lagrange two-way model. The liquid phase was solved using direct numerical simulation (DNS), and the particle motion was tracked by Newtonian equations of motion considering effects of drag force, pressure gradient force, and gravity. Two-way coupling was used to explain the effect of particles on the turbulence structure. The results show that the local void fraction of particles indicates the wall-peaked profile, particles scatter uniformly in the spanwise direction, and the injection of particles suppresses the turbulence activities in the near wall region. Suppression of the liquid turbulence is mainly caused by vortexes decay of different sizes.