Przemysl Chemiczny, Vol.91, No.3, 358-364, 2012
Determination of the enantiomeric purity and the in-process control by HPLC in the technology for production of optically active ingredients on an example of tolterodine tartrate
Applicability of the isocratic chiral high-performance liq. chromatog. with UV detection for detn. of the enantiomeric purity of active pharmaceutical ingredients was successfully tested on an example of (R)-2-[3-(diisopropylamino)1-phenylpropyl]-4-methylphenyl L-(+)-tartarate. Contents of both (R) and (S) isomers were detd.