The relationships between the morphologies and the permeability characteristics as dialysis membrane of polyether-segmented nylon 610 (PE-Ny610) have been investigated. PE-Ny610 used are poly(propylene oxide) (PPO)-segmented nylon 610 containing 25 wt % PPO (PPO-Ny610) and poly(ethylene oxide) (PEO)-segmented nylon 610 containing 15 wt % PEO(PEO-Ny610). The morphologies in the cross section of the membranes exhibit the cellular porous structures due to liquid-liquid phase separation. On the other hand, the structures of the surfaces are mainly composed of the crystalline spherulite due to liquid-solid phase separation. These morphologies are little affected by the composition ratio of the coagulant, calcium chloride/methanol/ water mixture. PEO-Ny610 membranes have shown superior membrane performances to the PPO-Ny610 membrane. The effect of PEO content in PEO-Ny610 on the adhesion of platelet onto the PEO-Ny610 film surface was investigated and it is concluded that PEO-Ny610 having > 10 wt % PEO shows a good nonthrombogenicity equal to PPO-Ny610.