A Lotus spreadsheet (LS) was utilized as part of a copolymerization study of methyl methacrylate (MMA) with N-phenylmaleimide (MP) and with some derivatives of MP, namely N-o-chlorophenylmaleimide (MOCP), N-p-tolylmaleimide (MPT), and N-o-tolylmaleimide (MOT). The use of LS provided a very rapid method to obtain values of copolymerization parameters which were in very good agreement with non-spreadsheet reported values. Further, a novel LS macro was developed which could be employed to ascertain the shape of the copolymer composition curve (copolymer composition as a function of monomer composition). Monomer reactivity ratios, r(1) and r(2), were determined as well as values of semi-empirical copolymerization parameters Q and e. An attempt was made to correlate the monomer structures used with the values of Q and e. An empirical decomposition temperature index (DTI) was also devised to measure the thermal stability of copolymers of MMA and MP as a function MP content.