In this paper, complementary thin-film transistor (TFT) inverter is fabricated with organic-inorganic hybrid channels. By adopting p-channel pentacene and n-channel ZnO, we have fabricated a device of hybrid complementary TFT inverter by using same electrode in organic-inorganic hybrid channels. To be accomplished Ohmic-contact in organic-inorganic hybrid channels, we adapted to n-channel staggered TFT and p-channel coplanar TFT. In results, a hybrid inverter built through integration of organic and inorganic TFT shows that the typical inverter response to stage switching is clearly observed between 0 and 40 V. for both input directions, displaying a high voltage gain (dV(OUT)/dV(IN))>16. (c) 2010 Elsevier B.V. All rights reserved.