Nanocomposite materials have been obtained by dispersing organic capped TiO2 nanocrystals (NCs) with different shape and surface chemistry in poly(methyl methacrylate) (PMMA) as a host medium. Films of the prepared nanocomposites based on TiO2 NCs have been fabricated by spin coating and morphologically characterized as a function of the preparative conditions. The organic vapor absorption ability of the PMMA/TiO2 NC based nanocomposites has been then investigated both for spherical and rod-like NCs, and the chemical nature of the coordinating organic molecules has been also varied. The results of the investigation have demonstrated that NC geometry and surface chemistry can modulate the specific absorption characteristics of the modified PMMA in order to absorb different solvent molecules (i.e. acetone, ethanol, propan-2-ol and water). Such features, due to specific interactions between the potential analyte vapors and the functionalized surface of NCs, can effectively be addressed in a controlled and reproducible way, thus offering original opportunities for designing innovative chemical sensors. (C) 2011 Elsevier B.V. All rights reserved.