(001)/(100) oriented PbTiO3 (PT) thin film is prepared on a non single crystal Indium Tin Oxide (ITO)/glass substrate by sol-gel method. The mechanism of orientation is investigated via dopant element, dopant amount, oxygen pressure of atmosphere, different type of substrate, different thickness of substrate, different sol concentration and blocking layer. By substituting 2% Zn2+, or 2% Fe3+, or 2% Co2+ ions in the Ti site of PT perovskite phase and heating at the oxygen-poor atmosphere, the PT thin film grown on the ITO(260 nm)/glass substrate forms well with (001)/(100) orientation. Moreover, this orientation phenomenon only appears when the solution concentration is below 0.1 mol/L. The orientation of PT which is attributed to the hybrid influences of defect dipole from the PT and the intrinsic electrostatic field from the ITO substrate is revealed. This work represents an important step toward controllable formation of oriented thin film on a non single crystal substrate. (C) 2011 Elsevier B.V. All rights reserved.