This experimental investigation focuses on the effects of angle of inclination on buoyancy-driven flows inside tall, rectangular, differentially-heated cavities. It considers a rectangular cavity with an aspect ratio of 28.6, with its two long sides maintained at different temperatures and the two short, end-walls, thermally insulated. The spanwise aspect ratio is 6.82 and the side walls are also thermally insulated. The Rayleigh number, based on the temperature difference and spacing between the long sides, is 0.86 x 10(6) for most cases and the working fluid is air (Prandtl number 0.71). Experimental data, for the flow and the thermal fields, using laser Doppler anemomentry and thermocouple traverses respectively, are presented for the cavity inclined at 60 degrees and 15 degrees to the horizontal, for both stable (the hot surface being the upper surface) and unstable orientations. The 15 degrees stable case is investigated at a higher Rayleigh number of 1.54 x 10(6) and some additional data for the 15 degrees unstable case are also presented at this higher value of Rayleigh number. For moderate angles of inclination, the flow is two-dimensional and the effects of inclination are primarily confined to the fluctuating fields. For large angles of inclination, the flow becomes three-dimensional. In the unstable 15 degrees angle of inclination case a set of four longitudinal vortices are formed over the entire length of the cavity, with four counter-rotating re-circulation cells within the cross-section parallel to the thermally active walls. The stable 15 degrees angle of inclination leads to the formation of two longitudinal vortices and two re-circulation cells. At the 15 degrees angle (stable and unstable), the enhanced mixing leads to uniform temperature in the cavity core and thus to only minor deviations from two-dimensionality in the thermal field. A modest rise in Rayleigh number, in the 15 degrees unstable case, does not affect the mean motion, but causes an increase in the normalised turbulence intensities. (C) 2012 Elsevier Ltd. All rights reserved.