Various copolyesters were synthesized by bulk polycondensation of the respective combinations of 1,4;3,6-dianhydro-D-glucitol (1) as the diol component and 1,1-bis [5-(methoxycarbonyl)-2-furyl] ethane (3b) and seven dimethyl dialkanoates with methylene chain lengths of 4, 5, 6, 7, 8, 10, and 12 (4a-4g) as the dicarboxylic acid components. Most of the copolyesters were amorphous, while a copolyester composed of 1, 3b, and dodecanedioic acid (4g) (3b:4g = 25:75) units as well as homopolyesters derived from 1 and azelaic acid (4d), sebacic acid (4e), and dodecandioic acid (4g), respectively, were partially crystalline. All these homo- and copolyesters were soluble in chloroform, dichloromethane, pyridine, trifluoroacetic acid, and m-cresol. The number-average molecular weights of these polyesters were estimated to be in the range of 10,000-20,000 by SEC using chloroform as an eluent and standard polystyrene as a reference. The biodegradability of these copolyesters was assessed by enzymatic degradation using four different enzymes in a phosphate buffer solution at 37 degrees C and by soil burial degradation tests in composted soil at 27 degrees C. In general, biodegradability of the copolyesters decreased with increase in the difuran dicarboxylate 3b content. Copolyesters containing sebasic acid 4e units showed higher biodegradability. Soil burial degradation in the soil that was treated with antibiotics, together with electron microscopic observation, indicated that actinomycetes are mainly responsible for the degradation of the copolyesters containing 3b units in the present soil burial test.