Steam reforming of methanol in fixed-bed and hybrid reactors, namely, traditional fixed-bed reactor (FBR1), fixed-bed reactor with H2-selective membrane (FBR2), and fixed-bed reactor with CO2 adsorption (FBR3) is thermodynamically analyzed. The performance of these reactors is compared in terms of quality and quantity of H2 production for fuel cell application. In FBR2 and FBR3, the contents of undesired products CO, CH4, and carbon are highly reduced.