The P-T-x-y data for tert-amyl methyl ether (TAME) separately with 2,2,4-trimethylpentane (TMP), methylcyclohexane (MCHX), and toluene were obtained at three temperatures, 293, 311, and 333 K. The vapor-liquid equilibria of a five-component mixture (TAME + TMP + 1-heptene + MCHX + toluene) at the same temperatures were measured as well. The data reported have been succesfully described using a Peng-Robinson equation of state with van der Waals one-fluid mixing rules.