Increasing concerns about the rising global warming and fluctuating crude oil prices have accelerated the research in a biobased economy over the past few years. In this regard, lactic acid (LA) is one of the major examples of biobased products and finds its applications in the bioplastic, pharmaceutical, and food industries and as a green solvent. LA production is mainly by the microbial fermentation of renewable feedstock. However, the feedstock produced per hectare for LA production has high seasonal variability, is in small quantity, and is distributed over a wide area. In addition, the LA produced within the fermentation broth is dilute and impure. These factors make the overall LA production process energy- and resource-intensive. This article proposes a compact and efficient reactive HiGee stripper-membrane (RI-ISM) process for industrial grade LA purification. Performance of the proposed RHSM is evaluated based on rigorous modeling and optimization followed by comparison with the conventional reactive stripper-membrane (RSM) process. The analysis in this work suggests that the designed RI-ISM plant can be placed on a commercial motor vehicle for on-farm LA purification.