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Journal of Chemical Engineering of Japan, Vol.30, No.4, 587-599, 1997
Artificial-Kidney Engineering - Dialysis Membrane and Dialyzer for Blood Purification
Since artificial organs are intended to replicate chemical processes, knowledge of chemical engineering is essential in their design so that they will function with the maximum efficiency. The most commonly used artificial organ is the artificial kidney, a machine that performs a treatment known as hemodialysis. This process cleanses the bodies of renal failure patients by dialysis and filtration which are simple physicochemical processes. Hemodialysis membranes act to remove accumulated uremic toxins, excess ions and water from the patient via the dialysate, and to supply from the dialysate those ions that are insufficient. This paper describes dialysis membranes and dialyzers for blood purification, the solute transport mechanism of the membrane, and a technical evaluation of the dialysis membrane. Lastly, the next generation of artificial kidney is reviewed.
Keywords:POLY(2-HYDROXYETHYL METHACRYLATE);HEMODIALYSIS MEMBRANES;MICROPOROUS MEMBRANES;SOLUTE PERMEABILITY;STRUCTURAL-ANALYSIS;WATER;COEFFICIENTS;PERMEATION;DIFFUSION;REJECTION