The in-situ study of chemical reactions is an intensively studied research topic. A suitable method for this investigation is the IR micro-imaging technique, which allows to record space- and time-resolved IR spectra. The preparation of a suitable model system with a 3D pore system for the in-situ recording of concentration profiles using IR micro-imaging is described, enabling the space- and time-resolved monitoring of catalytic reactions in nanoporous catalysts for the first time. The model system consists of a nanoporous glass monolith with gas-tight sealed outer surface, therefore, enabling the recording of concentration profiles of cyclohexane and cyclohexane-benzene mixtures as a function of time.