Chemistry Letters, Vol.42, No.10, 1151-1153, 2013
Asymmetric Conjugate Addition of Malonates to Enones Using Perfluorobutanesulfonamide Organocatalyst
Perfluorobutanesulfonamide organocatalyst 4 efficiently promotes asymmetric conjugate additions of malonates to alpha,beta-unsaturated ketones to afford the corresponding adducts with excellent enantioselectivities (up to 99% ee).