화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.22, No.3, 227-235, March, 2014
DOI10.1007/s13233-014-2045-6  Export Citation
Polyelectrolyte Hydrogels for Replacement and Regeneration of Biological Tissues
Hyuck Joon Kwon†, Kazunori Yasuda1, Jian Ping Gong2, and Yoshihiro Ohmiya3
  • Department of Physical Therapy, College of Health Science, Eulji University, Gyeonggi, 461-713, Korea
  • 1Department of Sports Medicine and Joint Surgery, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan
  • 2Laboratory of Soft and Wet Materials, Graduate School of Science, Hokkaido University, Sapporo, 060-0810, Japan
  • 3National Institute of Advanced Industrial Science and Technology, Ikeda, 563-8577, Japan
E-mail:
Polyelectrolyte gels are charged polymer networks with macro-ions fixed on the polymer chains. These gels have considerable potential for biological applications such as cellular scaffolds and the replacement of various biological tissues. Moreover, high strength up to several tens of megapascals can be obtained with polyelectrolyte gels by incorporating double network structure in the gel. This article gives a concise review to introduce the fundamental properties of polyelectrolyte gels and biological applications for tissue engineering using their characteristic properties. Applications of polyelectrolyte gels have been highlighted in the fields of artificial muscle, artificial corneas, artificial cartilage, scaffolds for in vitro stem cell culture, and scaffolds for in vivo cartilage regeneration. This review suggests that polyelectrolyte gels would be a useful material for the successful replacement and regeneration of damaged or diseased tissues.
Keywords:polyelectrolyte gel;bio-tissue replacement;artificial tissue;bio-tissue regeneration;stem cell.
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