화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.20, No.4, 1713-1719, July, 2014
DOI10.1016/j.jiec.2013.08.021  Export Citation
Biofabrication of gold nanoparticles and its biocompatibility in human breast adenocarcinoma cells (MCF-7)
Muralidharan Murugan1, Kevin John Pulikotil Anthony1, Muniyandi Jeyaraj1, Navanietha Krishnaraj Rathinam1, and Sangiliyandi Gurunathan1, 2, †
  • 1GS Center for Life Sciences, Gandhi Nagar, Sundarapuram, Coimbatore 641024, Tamilnadu, India
  • 2Department of Animal Biotechnology, Konkuk University, 1 Hwayang-Dong, Gwangin-gu, Seoul 143-701, Republic of Korea
E-mail:
In this paper, a simple and environmentally friendly method for synthesis of gold nanoparticles (AuNPs) using culture supernatant of Bacillus flexus as reductants and stabilizers is reported. The prepared AuNPs were characterized by various analytical techniques. UV-visible spectroscopy, X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS) results confirmed that Au3+ ions reduced into Au0. Fourier-transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) measurements confirmed that the chemical surface structure of AuNPs. TEM images showed the size and morphology of AuNPs. Moreover, the toxicity studies suggested that AuNPs were neither toxic nor inhibitory to human breast cancer cells (MCF-7).
Keywords:Bacillus flexus;Biocompatibility;Gold nanoparticles;Transmission electron microscopy;UV-visible spectroscopy
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