화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Journal of Chemical Engineering, Vol.31, No.8, 1377-1383, August, 2014
DOI10.1007/s11814-014-0077-4  Export Citation
Tetrabutylphosphonium amino acid ionic liquids as efficient catalysts for solvent-free Knoevenagel condensation reactions
Fan Ouyang, Yan Zhou, Zhang-Min Li, Na Hu, and Duan-Jian Tao†
  • College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China
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Five tetrabutylphosphonium amino acid ionic liquids ([P4444][AA]) were prepared, characterized, and used as catalysts for solvent-free Knoevenagel condensation reactions. The tetrabutylphosphonium prolinate ([P4444][Pro]) showed excellent catalytic activity and selectivity in Knoevenagel condensation reactions of active methylene compounds with various aromatic aldehydes, and all the yields of corresponding products were more than 85% under mild conditions. Furthermore, a plausible reaction mechanism for the excellent performance of [P4444][Pro] has been proposed, and [P4444][Pro] could be used repetitively at least six times without obvious decrease in activity and quantity.
Keywords:Ionic Liquid;Knoevenagel Condensation;Aromatic Aldehydes;Active Methylene Compounds;Amino Acid
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