Wearable human-interactive devices are advanced technologies that will improve the comfort, convenience, and security of humans, and have a wide range of applications from robotics to clinical health monitoring. In this study, a fully printed wearable human-interactive device called a smart bandage is proposed as the first proof of concept. The device incorporates touch and temperature sensors to monitor health, a drug-delivery system to improve health, and a wireless coil to detect touch. The sensors, microelectromechanical systems (MEMS) structure, and wireless coil are monolithically integrated onto flexible substrates. A smart bandage is demonstrated on a human arm. These types of wearable human-interactive devices represent a promising platform not only for interactive devices, but also for flexible MEMS technology.