Catalysis Letters, Vol.144, No.1, 172-180, 2014
Vanadium-Substituted Wells-Dawson Heteropolyacid as Catalyst for Liquid Phase Oxidation of 1,4-Dihydropyridine Derivative
H(7)P(2)W(17)VO(62 center dot)25H(2)O Wells-Dawson heteropolyacid was prepared, characterized and evaluated as catalyst in a 1,4-dihydropyridine oxidation reaction. The optimal conditions are the following: 1 mmol% of HWDV, a molar ratio 1,4-DHP:H2O2 (1:10) at reflux of acetonitrile. A conversion of 98.6 % is achieved in only 120 min of reaction.