화학공학소재연구정보센터
Chemistry Letters, Vol.43, No.6, 956-958, 2014
Efficient Glycosylation Using In(OTf)(3) as a Lewis Acid: Activation of N-Phenyltrifluoroacetimidate or Thioglycosides with Halogenated Reagents or PhIO
In(OTf)(3) efficiently activated N-phenyltrifluoroacetimidate and In(OTf)(3) in combination with various halogenated reagents or PhIO promoted glycosylation using thioglycoside in good yields. The combination with iodine interhalogens (e.g., ICl or IBr) effectively promoted alpha-sialylation.